Geptop:A Gene essentiality prediction tool for COMPLETE-GENOME based on orthology and phylogeny
Essential genes are absolutely required for the survival of an organism and are therefore considered the foundation of life. Geptop is a webserver, which first provides a platform to detect essential gene sets over bacterial species, by comparing orthology and phylogeny of query protein sets with essential gene datasets determined experimentally
(from DEG database).
You will get the possibilities of essentiality score for each gene, the number of predicted essential genes and the estimated accuracy for the genome
by our webserver.
How to cite the Geptop: Wei W, Ning LW, Ye YN, Guo FB*. (2013) Geptop: a gene essentiality prediction tool for sequenced bacterial genomes based on orthology and phylogeny. PLoS One. 8(8): e72343.
The new Geptop will coming soon!